HLA-B57:01 Products - Molecular genetics

Disease information

Genetic testing for HLA-B*57:01 is performed to prevent hypersensitivity reactions against the HIV chemopharmaceutic agent abacavir. Manifestations are fever, exanthema, pruritus, gastrointestinal and respiratory problems, joint pain and increased liver/kidney parameters with a progressive course up to death, especially with re-exposure. Therefore, it is recommended that all HIV-should be tested for the presence of the HLA-B*57:01 allele.

Diagnostic Guidelines

The EUROArray HLA-B57:01 Direct allows fast and simple molecular genetic determination of HLA-B*57:01 alleles in genomic DNA. All currently known HLA-B*57:01 alleles are detected in a single test run and the EUROArrays are automatically evaluated using the established EUROArrayScan software. The direct method allows the direct use of blood samples without prior time and cost-consuming DNA isolation.

HLA-B57:01 Direct products

For Research Use Only. Not For Use In Diagnostic Procedures.
The individual product regulatory statements may vary, please refer to the instructions for use for more information.

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